Prof. Dr. John A. Murphy Professor, University of Strathclyde Trinity College, Dublin (BA 1976) University of Cambridge (PhD 1980) DSc 2002 *Art by graphic artist Maxime Py and the Super-Kamiokande Collaboration! Electron Fiddle lets you create and play with small Electron experiments. (b) Characterization of Super Electron Donors (ref. The latter represent very electron-rich compounds with a low ionization energy. Reference or 0-3—0' Complex 2 , so o Complex 1 MeO rt Traditionally, these species undergo two electron reactions, acting as nucleophiles. 4): (Electron Acceptor) Super electron donors in the diboron/methoxide/pyridine system were isolated and characterized. In the past decade, a host of exceptionally strong organic electron donors has been designed and prepared; their redox potentials are more negative than any previous neutral organic donors and extend beyond E 1/2 = −1 V vs. the saturated calomel electrode (SCE). 2007, 5178 SET O CO2Et Me Me O CO2Et Me Me TAF2 BPL (8%) (83%) TAF1 (77%) 27 30 31 DET? Another area of focus has been strong neutral electron donors, termed "super-electron-donors". Excess sodium hydride has a very beneficial effect on yields of products in certain cases, and a rationale for this has been proposed. Organic electron donors are of importance for a number of applications. Perspective: Murphy, J. CHIMIA, 66 (6). Super electron donors powerful reductions performed by neutral organic molecules Author: Schonebeck, Franziska ISNI: 0000 0001 3556 6598 ... called Super-S.E.T. Here, we analyze these factors in detail. Neutral organic donors that can reduce aryl halides have been termed “super-electron-donors”. These reagents, called super electron donors, are on track to become important synthetic tools for organic chemists. Ed., 2007, 46, 5178-5183. They can be converted into stable radical cations via one-electron oxidations using, e.g., chloroform or benzyl bromide as oxidants. However, the factors that are essential for a directed design of compounds with desired reduction power are not clear. Neutral organic super-electron donors can be used as reducing agents for the cleavage of N-O bonds in Weinreb amides. Chemical reactivity promoted by electron transfer is one of the major areas of chemistry. The latter represent very electron-rich compounds with a low ionization energy. J. Org. Strong neutral electron donors, termed "super-electron-donors", are characterized by low ionization energies and very negative oxidation potentials (E 1/2 values beyond –1 V vs. SCE). Perspective on super electron donors: Murphy, J. Org. The donors show evidence for transfer of one electron or two electrons, dependent on their structure. Super-electron-donors. 2014, 3731 Perspective on super electron donors: Murphy, Chem. We now know that simple neutral organic molecules: (i) can reduce aryl halides to organic radicals or organic anions. However, the factors that are essential for a directed design of compounds with desired reduction power are not clear. Chem. Then, save your Fiddle either as a GitHub Gist or to a local folder. Try more powerful experiments with Electron Fiddle. Our recent research has exam-ined the remarkable chemical reactivity of such donors 1 and 2 as well as the related electron-donors 4 and 5 (Figure€1), with organic substrates [17-27]. Benzimidazole-derived donor 1 Here, we analyze these factors in detail. Neutral organic super electron donors (SEDs) display impressive reducing power but, until now, it has not been possible to use them catalytically in radical chain reactions. Chem. 10 12) and the trapped species 12 is then not available for further useful chemistry. Super Electron Donors Derived From Diboron Li Zhang and Lei Jiao* Center of Basic Molecular Science (CBMS), Department of Chemistry, Tsinghua University, Beijing 100084, China Leijiao@mail.tsinghua.edu.cn Contents 1. Hybrid organic super-electron-donors have been prepared, and their reactivity with aryl iodides tested. Commun. reagent 1, that allows the reduction of unactivated aryl and alkyl iodides. Int. My study investigates the scope of donor 1 as a reducing agent and extends the study to a more powerful donor 2. Abstract. 418-424.. Full text not available in this repository.Request a copy from the Strathclyde author Abstract. S1 Organic Super-Electron-Donors: Initiators in Transition Metal-Free Haloarene-Arene Coupling Shengze Zhou,1 Greg M. Anderson,1 Bhaskar Mondal,1 Eswararao Doni,1 Vicki Ironmonger,2 2Michael Kranz, Tell Tuttle1* and John A. Murphy1* Supplementary Information From gas- phase ionization energies to solution oxidation potentials: Dimolybdenum tetraformamidinate paddlewheel complexes. In the past decade, a host of exceptionally strong organic electron donors has been designed and prepared; their redox potentials are more negative than any previous neutral organic donors and extend beyond E1/2 = −1 V vs. the saturated calomel electrode (SCE). Ed. A general and practical organocatalytic radical generation strategy was developed based on mechanistic study results. The electron transport chain (ETC) is a series of protein complexes that transfer electrons from electron donors to electron acceptors via redox reactions (both reduction and oxidation occurring simultaneously) and couples this electron transfer with the transfer of protons (H + ions) across a membrane.The electron transport chain is built up of peptides, enzymes, and other molecules. A. Cyclic voltammetry (CV) studies showed that the more powerful donors, e.g., 2 [ 15 – 16 18 ] and 4 [ 19 ], lose their second electrons at almost the same potential as their first electron ( Fig. Organic super-electron-donors: initiators in transition metal-free haloarene–arene coupling Organic super-electron-donors: initiators in transition metal-free haloarene–arene coupling Zhou, Shengze; Anderson, Greg M.; Mondal, Bhaskar; Doni, Eswararao; Ironmonger, Vicki; Kranz, Michael; Tuttle, Tell; Murphy, John A. The latter represent very electron-rich compounds with a low ionization energy. In this paper, we provide a solution to this longstanding issue by altering the nature of the super electron donors… In this chemistry, deprotonation of benzophenone ketimines generates 2-azaallyl anions (A0). Super-electron-donors and related compounds. Organic electron donors Super electron donors : SET v.s. The team found that the products are a new class of organic super-electron-donors: They have a low ionization energy and can easily transfer a single electron. The scope of neutral organic super-electron donors as reducing agents has been extended to include the reductive cleavage of N-O bonds in Weinreb amides. The diboron/methoxide/pyridine system enables the preparation of organic super electron donors from easily accessible starting materials under mild conditions, which has the potential to be a general and practical single-electron reducing agent in organic synthesis. Int. Chem. DET N N N N MeMe N N N N N N Me 2N NMe 2 TAF1 TAF2 BPL O I CO2Et Me Me Super electron donors DMF, Δ OMe Me O H CO2Et Me Me O (21%) (51%) J. Discovery and Development of Organic Super-Electron-Donors. The reaction of nitrous oxide (N2O) with N-heterocyclic olefins (NHOs) results in cleavage of the N–O bond and formation of azo-bridged NHO dimers. Abstract. Cyclic voltammetry studies show that the dimers can be classified as new organic super-electron-donors, with a reducing power similar to what is found for tetraazafulvalene derivatives. Dimetal paddlewheel complexes with bicyclic guanidine ligands are extremely strong thermodynamic electron donors. These are characterized by low ionization energies and very negative oxidation potentials (E 1/2 values beyond –1 V vs. SCE). It greets you with a quick-start template after opening – change a few things, choose the version of Electron you want to run it with, and play around. As a probe of the chemical potential and sites for chemical reactivity of these complexes, the interaction of Mo 2 (TEhpp) 4 with weak acids was investigated (TEhpp is the anion of the bicyclic guanidine 3,3,9,9-tetraethyl-1,5,7-triazabicyclo[4.4.0. These include the discovery of 2-azaallyl anions as super electron donors (SEDs). Organic electron donors are of importance for a number of applications. 2 includes the CV of 4 , showing a single two-electron redox wave, while Fig. This methodology proved to be applicable to a large array of substrates to afford their reduced counterparts in good yields. super electron donors 3-6, trapping occurs on carbon (e.g. By Van Dorn, Laura O.; Borowski, Susan C.; Lichtenberger, Dennis L. From Inorganica Chimica Acta, 2015, 424, 316-321. Chem. pp. ]dec-4-ene). The pyridinylidene–benzimidazolylidene and imidazolylidene–benzimidazolyli-dene hybrid systems were designed to be the first super electron donors to convert iodoarenes to aryl radicals at room temperature, and indeed both show evidence for significant aryl radical formation at room temperature. Electron donors play a dominant role in determining the behavior of super high activity (MgCl 2-supported) catalysts for polypropylene.This is particularly so in systems in which the internal donor is a phthalate ester and where an alkoxysilane or hindered amine is used as external donor. A. Murphy, Angew. OMe Me O OEt T (0%) 32 28 29 19 Hybrid super electron donors – preparation and reactivity By Jean Garnier, Douglas W Thomson, Shengze Zhou, Phillip I Jolly, Leonard E A Berlouis and John A Murphy Cite 4 includes that of 2 ). Zhou, Sheng-Ze and Farwaha, Hardeep and Murphy, John A () The development of organic super electron donors. 2014, 79, 3731-3746.! These reagents, called super electron donors, are on track to become important synthetic tools for organic chemists. Angew. (ii) can reduce benzenes in the presence of malonates and cyanoacetates. [8] This impedes the use of donors 3-6 in radical chain reactions. The reaction of nitrous oxide (N2O) with N-heterocyclic olefins (NHOs) results in cleavage of the N–O bond and formation of azo-bridged NHO dimers. Organic Molecules (Super-Electron-Donors) as Reducing Agents.