We have a record for a David A Horn living at an address in Dundee DD5. 36: 2608-2618. 7. In a paper published in Nature Microbiology, David Horn, Professor of Parasite Molecular biology in the Wellcome Centre for Anti-Infectives Research, said that the findings represent a major advance. 1. ), Marketa Novotna (Wellcome PhD), Gustavo Ruiz (from Uni. The University of Dundee’s Professor David Horn has received a prestigious award in recognition of his contribution to global efforts to overcome the disease known as African sleeping sickness. Our research is supported by the Wellcome Trust and the Medical Research Council and DH is a Wellcome Trust Senior Investigator. In a paper published in Nature Microbiology, David Horn, Professor of Parasite Molecular biology in the Wellcome Centre for Anti-Infectives Research, said that the findings represent a major advance. Cell 52:554-565. 5. Welcome to Melanie Ridgway (from Australian Nat. USA.113:7225-30. They are masters of antigenic variation and immune evasion in the host bloodstream. USA.113:7225-30. ... Spune-ţi părerea despre David Horn Pentru a scrie un review trebuie sa fii autentificat. We also seek to understand drug action and resistance. African trypanosomes are parasitic protists which cause sleeping sickness or Human African Trypanosomiasis (HAT) and the livestock disease, nagana. 112:9112-9117. Mattie Pawlowic (Participant) & David Horn (Participant) 6 Mar 2019 → 7 Mar 2019. His research is focused on antigenic variation, drug action and resistance and the application of genetic screens to the African trypanosome, Trypanosoma brucei. ), Marketa Novotna (Wellcome PhD), Gustavo Ruiz (from Uni. 6. We have found at least 200 people in the UK with the name David Horn. 115 Art works. See the complete profile on LinkedIn and discover David’s connections and jobs at similar companies. Baker N, Hamilton G, Wilkes J, Hutchinson S, Barrett MP, Horn D. (2015) Vacuolar ATPase depletion affects mitochondrial ATPase function, kinetoplast dependency and drug-sensitivity in trypanosomes. Genealogy for George Browne Provost of Dundee & Horn (deceased) family tree on Geni, with over 190 million profiles of ancestors and living relatives. USA. David Horn, Professor of Parasite Molecular Biology and Deputy Director of WCAIR and the Division of Biological Chemistry and Drug Discovery was recently awarded the William Trager award by the American Committee of Molecular, Cellular and Immunoparasitology (ACMCIP). The World Health Organization’s target is to stop sleeping sickness transmission by 2030. We also seek to understand drug action and resistance. Published on 21 November 2019 Mony BM, MacGregor P, Ivens A, Rojas F, Cowton A, Wilson J, Horn D and Matthews KR (2014) Genome wide dissection of the quorum sensing signaling pathway in Trypanosoma brucei. Our exploitation of genome sequence data is underpinned by technology development. Alsford S, Eckert S, Baker N, Glover L, Sanchez-Flores A, Leung K, Turner DJ, Field MC, Berriman M and Horn D.(2012) High-throughput decoding of antitrypanosomal drug efficacy and resistance. David Horn is rated #65 out of 64 halls at University of Edinburgh. David Horn's 220 research works with 6,658 citations and 4,337 reads, including: Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes Click here to find personal data about David Horn including phone numbers, addresses, directorships, electoral roll information, related property prices and other useful information. Cells. Over the last seventeen years, I’ve had the great fortune to learn from and work with amazing and brilliant people. “We reported our discovery of the VEX1 protein in 2016 and the VEX2 protein in 2019” he said. The World Health Organization’s target is to stop sleeping sickness transmission by 2030. University of Dundee VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes Glover, Lucy; Hutchinson, Sebastian; Alsford, Sam; Horn, David The original oil paintings, watercolours and mixed media of the artist David Horn ARCA Antigenic variation, drug resistance and RNAi screens in trypanosomes. Benzoxaboroles are under development for these lethal diseases and show great promise in clinical and veterinary trials. Full Telephone: +44 (0) 1382 386286, int ext 86286. Natl Acad. There are 1,000+ professionals named "David Horn", who use LinkedIn to exchange information, ideas, and opportunities. Rio). Welcome to Melanie Ridgway (from Australian Nat. View the profiles of people named David Horn. Uni. Glover L, McCulloch R andHorn D. (2008) Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes. Cell. Telephone +44 (0)1582 490300. Suramin uptake was shown to be via receptor (ISG75)-mediated endocytosis while an aquaglyceroporin (AQP2) controls melarsoprol-pentamidine cross-resistance; AQP2 has now also been linked to clinical cases of melarsoprol resistance. Genome Research. Sci. We recently identified >50 genes linked to drug action. Reviews take into account everything from value for money, hall management, cleaning services, social experience & wifi. 10. Horn Dand Cross GAM. 2. Baker N, Glover L, Munday JC, Aguinaga Andrés D, Barrett MP, de Koning HP, and Horn D.(2012) Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes.Proc. Support Wright Memorial Medal from the British Society for Parasitology. Suramin uptake was shown to be via receptor (ISG75)-mediated endocytosis while an aquaglyceroporin (AQP2) controls melarsoprol-pentamidine cross-resistance; AQP2 has now also been linked to clinical cases of melarsoprol resistance. Aberdeen) and Douglas Escrivani (from Uni. 109:10996–11001. Natl Acad. Rudd SG, Glover L, Jozwiakowski SK, Horn D and Doherty AJ (2013) PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome.Mol. Sci. The award recognises scientists who have made substantial contributions in the field of basic parasitology. Professor Ian Gilbert Head of Chemistry Drug Discovery Unit and WCAIR Gilbert lab website Professor Antigenic variation, drug resistance and RNAi screens in trypanosomes, School of Life Sciences, University of Dundee, Dundee, William Trager Award for Basic Parasitology (2019), Fellow of the Royal Society of Edinburgh (2017), Wellcome Trust Senior Investigator Award (2012), Wellcome Centre for Anti-Infectives Research (WCAIR), Parasite defence mechanism de-coded by Dundee research team, Award recognises ‘transformative’ research, £2.1 million Wellcome Investigator award for Dundee scientist, China Scholarship Council PhD programme - Anti-parasitic drugs: Mechanisms and protein modifications, MRC DTP: Understanding genetic mechanisms underpinning drug sensitivity in parasitic diseases, Wellcome 4-Year PhD Programme in Integrated Molecular, Cellular and Translational Biology. 192.com has records on millions of UK people and addresses. 3. SC015096. Professor David Horn, of the School of Life Sciences at the University of Dundee, is to be awarded the prestigious C.A. © University of Dundee, View full research profile and publications, Parasite defence mechanism de-coded by Dundee research team, Award recognises ‘transformative’ research. View David Horne’s profile on LinkedIn, the world’s largest professional community. The University of Dundee’s Professor David Horn has received a prestigious award in recognition of his contribution to global efforts to overcome the disease known as African sleeping sickness. Cells were cultured in HMI-9 at 37 o C with 5% CO 2. J. David Horne, P.E. Professor David Horn FRSE Professor of Parasite Molecular Biology Antigenic variation, drug resistance and RNAi screens in trypanosomes : Professor Bill Hunter FRSE, FMedSci, FRSC Professor of Structural Biology Protein structure and function; fundamental chemical biology and early stage antimicrobial drug discovery : Dr Mattie Pawlowic 10 11 * For correspondence: d.horn@dundee.ac.uk; Tel: +44 1382 386286 12 View the profiles of professionals named "David Horne" on LinkedIn. Current challenges include a shortage of safe, affordable, and efficacious drugs, as well as veterinary reservoirs of trypanosomes, which themselves cause livestock disease. We have found at least 200 people in the UK with the name David Horn. Nucleic Acids Res.39: 1372-1380. Aberdeen) and Douglas Escrivani (from Uni. I use Lister 427, MITat 1.5 (clone 118a) and MITat 1.2 (clone 221a) (2, 3). “We reported our discovery of the VEX1 protein in 2016 and the VEX2 protein in 2019” he said. Benzoxaboroles are under development for these lethal diseases and show great promise in clinical and veterinary trials. Current challenges include a shortage of safe, affordable, and efficacious drugs, as well as veterinary reservoirs of trypanosomes, which themselves cause livestock disease. David Horn Communications Limited Comtec House Bramingham Business Park Enterprise Way LUTON LU3 4BU United Kingdom. Click here to find personal data about David Horn including phone numbers, addresses, directorships, electoral roll information, related property prices and other useful information. Nature. The award recognises scientists who have made substantial contributions in the field of basic parasitology. Scottish Registered Charity, No. 1 talking about this. Nature. David Horn's 225 research works with 7,084 citations and 4,192 reads, including: Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs Join Facebook to connect with David Horn and others you may know. (1995) A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei. 21: 915-924. A team at the University of Dundee has identified how random genetic decisions allow parasites to survive in their human and animal hosts. Email (Sales and Technical) sales@dhcltd.co.uk. David has 11 jobs listed on their profile. The University of Dundee’s Professor David Horn has received a prestigious award in recognition of his contribution to global efforts to overcome the disease known as African sleeping sickness. [Click here for HMI-11 recipe and additional info']. We recently identified >50 genes linked to drug action. (2011) High throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome. The University of Dundee’s Professor David Horn has received a prestigious award in recognition of his contribution to global efforts to overcome the disease known as African sleeping sickness. sloop, 1826 taken over from Dundee & Perth Shipping Co., 1826 driven ashore at Great Ormes Head, North Wales, 1827 refloated but condemned and sold at auction to Horn & Hayes, Wexford. Engineering Field. Wright Memorial Medal from the British Society for Parasitology. David Horn, 10 December 2001. 482: 232-236. There are 500+ professionals named "David Horne", who use LinkedIn to exchange information, ideas, and opportunities. Professor David Horn FRSE. Related News. Proc. 4 Laura Jeacock, Joana Faria and David Horn* 5 6 Short title: Codon usage controls gene expression in trypanosomes 7 8 Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University 9 of Dundee, Dow Street, Dundee DD1 5EH, UK. [Use 221a if you have no preference - it grows faster!] Unfortunately, melarsoprol-resistant parasites emerged as ea … On this page. Vezi profilurile persoanelor care poartă numele de David Horn. Helen Mirren to Receive Career Achievement Honor at Aarp The Magazine's Movies For Grownups Awards View the profiles of professionals named "David Horn" on LinkedIn. Rio). Civil/Structural Mr. Horne is a hands-on engineer. Read reviews from current & past students for David Horn at University of Edinburgh. Sci. The record includes the full address, along with information about the source of the data that will show whether the address is likely to be current. David Witteveen (born 5 May 1985 in Varese, Italy) is an Austrian footballer.He plays as a striker and is currently playing for SC Ritzing.. Career. In particular, we have developed an RNAi library screening method called RNA Interference Target sequencing or RIT-seq. Glover L, Jun J andHorn D. (2011) Microhomology mediated deletion and gene conversion in African trypanosomes. USA. The University of Dundee’s Professor David Horn has received a prestigious award in recognition of his contribution to global efforts to overcome the disease known as African sleeping sickness. Activity: Participating in or organising an event types › Participation in conference. 99: London (1) 1824: smack, 1826 taken over from Dundee & Perth Shipping Co., 1847 sold to R. Tosh, Dundee and rigged as schooner. Prof. David Horn is a Wellcome Trust Senior Investigator and Professor of Parasite Molecular Biology in the School of Life Sciences. Discovery - the University of Dundee Research Portal contact form. Fairlamb Alan H, Horn David Trends Parasitology Volume 34, Issue 6, June 2018, Pages 481-492 Arsenical monotherapies were previously very.. Read More Inducible high-efficiency CRISPR-Cas9-targeted gene editing and precision base editing in African trypanosomes. David Horn, Producer: Great Performances. Proc. One goal is to understand the molecular mechanisms underlying this process. Sci. David Horn, Professor of Parasite Molecular Biology and Deputy Director of WCAIR and the Division of Biological Chemistry and Drug Discovery was recently awarded the William Trager award by the American Committee of Molecular, Cellular and Immunoparasitology (ACMCIP). Horn, David Professor 取消收藏 收藏 完善纠错 ... University of Dundee School of Life Sciences ... Alsford S, Horn D. (2016) VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes. 4. David Horn's 225 research works with 7,084 citations and 4,192 reads, including: Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs Our research is supported by the Wellcome Trust and the Medical Research Council and DH is a Wellcome Trust Senior Investigator. Natl Acad. Glover L, Hutchinson S, Alsford S, Horn D. 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